Tertiary motifs as building blocks for the design of protein‐binding peptides
Despite advances in protein engineering, the de novo design of small proteins or peptides that bind to a desired target remains a difficult task. Most computational methods search for binder structures in a library of candidate scaffolds, which can lead to designs with poor target complementarity an...
Main Authors: | Swanson, Sebastian, Sivaraman, Venkatesh, Grigoryan, Gevorg, Keating, Amy E |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Wiley
2022
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Online Access: | https://hdl.handle.net/1721.1/144152 |
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