Compact RNA editors with small Cas13 proteins
CRISPR-Cas13 systems have been developed for precise RNA editing, and can potentially be used therapeutically when temporary changes are desirable or when DNA editing is challenging. We have identified and characterized an ultrasmall family of Cas13b proteins-Cas13bt-that can mediate mammalian trans...
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Bibliographic Details
| Main Authors: |
Kannan, Soumya,
Altae-Tran, Han,
Jin, Xin,
Madigan, Victoria J,
Oshiro, Rachel,
Makarova, Kira S,
Koonin, Eugene V,
Zhang, Feng |
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| Other Authors: |
Howard Hughes Medical Institute |
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| Format: | Article
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| Language: | English |
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| Published: |
Springer Science and Business Media LLC
2022
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| Online Access: | https://hdl.handle.net/1721.1/144412
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