Compact RNA editors with small Cas13 proteins

Compact RNA editors with small Cas13 proteins

CRISPR-Cas13 systems have been developed for precise RNA editing, and can potentially be used therapeutically when temporary changes are desirable or when DNA editing is challenging. We have identified and characterized an ultrasmall family of Cas13b proteins-Cas13bt-that can mediate mammalian trans...

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Bibliographic Details
Main Authors: Kannan, Soumya, Altae-Tran, Han, Jin, Xin, Madigan, Victoria J, Oshiro, Rachel, Makarova, Kira S, Koonin, Eugene V, Zhang, Feng
Other Authors: Howard Hughes Medical Institute
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2022
Online Access:https://hdl.handle.net/1721.1/144412

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