A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes
Palladium oxidative addition complexes (OACs) have recently emerged as useful tools to enable challenging bond connections. However, each OAC can only be formed with one dative ligand at a time. As no one ligand is optimal for every cross-coupling reaction, we herein disclose a ligand exchange proto...
| Main Authors: | , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society (ACS)
2022
|
| Online Access: | https://hdl.handle.net/1721.1/144413 |
| _version_ | 1811084929929314304 |
|---|---|
| author | King, Ryan P Krska, Shane W Buchwald, Stephen L |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry King, Ryan P Krska, Shane W Buchwald, Stephen L |
| author_sort | King, Ryan P |
| collection | MIT |
| description | Palladium oxidative addition complexes (OACs) have recently emerged as useful tools to enable challenging bond connections. However, each OAC can only be formed with one dative ligand at a time. As no one ligand is optimal for every cross-coupling reaction, we herein disclose a ligand exchange protocol for the preparation of a series of OACs bearing a variety of ancillary ligands from one common complex. These complexes were further applied to cross-coupling transformations. |
| first_indexed | 2024-09-23T12:59:52Z |
| format | Article |
| id | mit-1721.1/144413 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T12:59:52Z |
| publishDate | 2022 |
| publisher | American Chemical Society (ACS) |
| record_format | dspace |
| spelling | mit-1721.1/1444132023-01-20T18:10:30Z A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes King, Ryan P Krska, Shane W Buchwald, Stephen L Massachusetts Institute of Technology. Department of Chemistry Palladium oxidative addition complexes (OACs) have recently emerged as useful tools to enable challenging bond connections. However, each OAC can only be formed with one dative ligand at a time. As no one ligand is optimal for every cross-coupling reaction, we herein disclose a ligand exchange protocol for the preparation of a series of OACs bearing a variety of ancillary ligands from one common complex. These complexes were further applied to cross-coupling transformations. 2022-08-22T16:57:35Z 2022-08-22T16:57:35Z 2021 2022-08-22T16:49:33Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/144413 King, Ryan P, Krska, Shane W and Buchwald, Stephen L. 2021. "A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes." Organic Letters, 23 (15). en 10.1021/ACS.ORGLETT.1C02101 Organic Letters Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf American Chemical Society (ACS) PMC |
| spellingShingle | King, Ryan P Krska, Shane W Buchwald, Stephen L A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes |
| title | A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes |
| title_full | A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes |
| title_fullStr | A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes |
| title_full_unstemmed | A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes |
| title_short | A Ligand Exchange Process for the Diversification of Palladium Oxidative Addition Complexes |
| title_sort | ligand exchange process for the diversification of palladium oxidative addition complexes |
| url | https://hdl.handle.net/1721.1/144413 |
| work_keys_str_mv | AT kingryanp aligandexchangeprocessforthediversificationofpalladiumoxidativeadditioncomplexes AT krskashanew aligandexchangeprocessforthediversificationofpalladiumoxidativeadditioncomplexes AT buchwaldstephenl aligandexchangeprocessforthediversificationofpalladiumoxidativeadditioncomplexes AT kingryanp ligandexchangeprocessforthediversificationofpalladiumoxidativeadditioncomplexes AT krskashanew ligandexchangeprocessforthediversificationofpalladiumoxidativeadditioncomplexes AT buchwaldstephenl ligandexchangeprocessforthediversificationofpalladiumoxidativeadditioncomplexes |