Multi-Omics Investigation to on the Effect of Replication Stress on Leukemia Cells
Differentiation therapy has the potential to treat cancers like acute myeloid leukemia. While the DHODH inhibitor has been shown to induce differentiation in an AML model, the mechanism that this happens is still unknown. Here we characterize a similar differentiation phenotype in the CML cell line...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/144682 |