Noncanonical recognition and degradation of a stable soluble protein by AAA protease FtsH

Noncanonical recognition and degradation of a stable soluble protein by AAA protease FtsH

AAA+ (ATPases associated with various cellular activities) proteolytic machines help maintain and adjust the cellular proteome in response to stress or changes in nutrients. AAA+ proteases bind degradation targets and utilize ATP-powered conformational changes in the AAA+ unfoldase ring to denature...

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Bibliographic Details
Main Author:	Morehouse, Juhee P.
Other Authors:	Sauer, Robert T.
Format:	Thesis
Published:	Massachusetts Institute of Technology 2022
Online Access:	https://hdl.handle.net/1721.1/144887

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