Catalytic Reactions of Organoboranes
Organoboranes represent a privileged class of intermediates and are integral to the syntheses of numerous medicinally relevant molecules. The synthesis of organoboranes is usually through 2 electron polar methods which often involve expensive and toxic reagents used in stoichiometric quantities. We...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/145091 |
| _version_ | 1811077523602145280 |
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| author | Seim, Alexander |
| author2 | Willard, Adam P. |
| author_facet | Willard, Adam P. Seim, Alexander |
| author_sort | Seim, Alexander |
| collection | MIT |
| description | Organoboranes represent a privileged class of intermediates and are integral to the syntheses of numerous medicinally relevant molecules. The synthesis of organoboranes is usually through 2 electron polar methods which often involve expensive and toxic reagents used in stoichiometric quantities. We proposed that 1 electron radical chemistry can be used to generate new organoboranes under catalytic systems to allow for more controllable and efficient processes. Herein we report our efforts towards developing new catalytic methodologies for the synthesis of organoboranes. |
| first_indexed | 2024-09-23T10:44:23Z |
| format | Thesis |
| id | mit-1721.1/145091 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T10:44:23Z |
| publishDate | 2022 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/1450912022-08-30T03:47:02Z Catalytic Reactions of Organoboranes Seim, Alexander Willard, Adam P. Massachusetts Institute of Technology. Department of Chemistry Organoboranes represent a privileged class of intermediates and are integral to the syntheses of numerous medicinally relevant molecules. The synthesis of organoboranes is usually through 2 electron polar methods which often involve expensive and toxic reagents used in stoichiometric quantities. We proposed that 1 electron radical chemistry can be used to generate new organoboranes under catalytic systems to allow for more controllable and efficient processes. Herein we report our efforts towards developing new catalytic methodologies for the synthesis of organoboranes. S.M. 2022-08-29T16:32:16Z 2022-08-29T16:32:16Z 2022-05 2022-06-08T13:05:32.672Z Thesis https://hdl.handle.net/1721.1/145091 In Copyright - Educational Use Permitted Copyright MIT http://rightsstatements.org/page/InC-EDU/1.0/ application/pdf Massachusetts Institute of Technology |
| spellingShingle | Seim, Alexander Catalytic Reactions of Organoboranes |
| title | Catalytic Reactions of Organoboranes |
| title_full | Catalytic Reactions of Organoboranes |
| title_fullStr | Catalytic Reactions of Organoboranes |
| title_full_unstemmed | Catalytic Reactions of Organoboranes |
| title_short | Catalytic Reactions of Organoboranes |
| title_sort | catalytic reactions of organoboranes |
| url | https://hdl.handle.net/1721.1/145091 |
| work_keys_str_mv | AT seimalexander catalyticreactionsoforganoboranes |