Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?

<jats:p>Following the approval by the FDA of two COVID-19 vaccines, which are administered in two doses three to four weeks apart, we simulate the effects of various vaccine distribution policies on the cumulative number of infections and deaths in the United States in the presence of shocks t...

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Main Authors: Ben Chaouch, Zied, Lo, Andrew W., Wong, Chi Heem
Other Authors: Sloan School of Management. Laboratory for Financial Engineering
Format: Article
Published: Public Library of Science (PLoS) 2022
Online Access:https://hdl.handle.net/1721.1/145512
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author Ben Chaouch, Zied
Lo, Andrew W.
Wong, Chi Heem
author2 Sloan School of Management. Laboratory for Financial Engineering
author_facet Sloan School of Management. Laboratory for Financial Engineering
Ben Chaouch, Zied
Lo, Andrew W.
Wong, Chi Heem
author_sort Ben Chaouch, Zied
collection MIT
description <jats:p>Following the approval by the FDA of two COVID-19 vaccines, which are administered in two doses three to four weeks apart, we simulate the effects of various vaccine distribution policies on the cumulative number of infections and deaths in the United States in the presence of shocks to the supply of vaccines. Our forecasts suggest that allocating more than 50% of available doses to individuals who have not received their first dose can significantly increase the number of lives saved and significantly reduce the number of COVID-19 infections. We find that a 50% allocation saves on average 33% more lives, and prevents on average 32% more infections relative to a policy that guarantees a second dose within the recommended time frame to all individuals who have already received their first dose. In fact, in the presence of supply shocks, we find that the former policy would save on average 8, 793 lives and prevents on average 607, 100 infections while the latter policy would save on average 6, 609 lives and prevents on average 460, 743 infections.</jats:p>
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spelling mit-1721.1/1455122022-09-29T11:22:05Z Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals? Ben Chaouch, Zied Lo, Andrew W. Wong, Chi Heem Sloan School of Management. Laboratory for Financial Engineering Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Sloan School of Management <jats:p>Following the approval by the FDA of two COVID-19 vaccines, which are administered in two doses three to four weeks apart, we simulate the effects of various vaccine distribution policies on the cumulative number of infections and deaths in the United States in the presence of shocks to the supply of vaccines. Our forecasts suggest that allocating more than 50% of available doses to individuals who have not received their first dose can significantly increase the number of lives saved and significantly reduce the number of COVID-19 infections. We find that a 50% allocation saves on average 33% more lives, and prevents on average 32% more infections relative to a policy that guarantees a second dose within the recommended time frame to all individuals who have already received their first dose. In fact, in the presence of supply shocks, we find that the former policy would save on average 8, 793 lives and prevents on average 607, 100 infections while the latter policy would save on average 6, 609 lives and prevents on average 460, 743 infections.</jats:p> 2022-09-20T12:24:19Z 2022-09-20T12:24:19Z 2022-07-01 Article http://purl.org/eprint/type/JournalArticle 2767-3375 https://hdl.handle.net/1721.1/145512 Ben Chaouch, Zied, Lo, Andrew W. and Wong, Chi Heem. 2022. "Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?." 2 (7). 10.1371/journal.pgph.0000498 Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf Public Library of Science (PLoS) PLoS
spellingShingle Ben Chaouch, Zied
Lo, Andrew W.
Wong, Chi Heem
Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_full Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_fullStr Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_full_unstemmed Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_short Should we allocate more COVID-19 vaccine doses to non-vaccinated individuals?
title_sort should we allocate more covid 19 vaccine doses to non vaccinated individuals
url https://hdl.handle.net/1721.1/145512
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