Palladium–peptide oxidative addition complexes for bioconjugation
<jats:p>Peptides bearing palladium oxidative addition complexes can be synthesized from the parent aryl halide containing substrates and react with thiol functional groups of small molecules, peptides, and proteins at low micromolar concentrations.</jats:p>
| Main Authors: | , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry (RSC)
2022
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| Online Access: | https://hdl.handle.net/1721.1/146551 |
| _version_ | 1811093128570994688 |
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| author | Rojas, Anthony J Wolfe, Justin M Dhanjee, Heemal H Buslov, Ivan Truex, Nicholas L Liu, Richard Y Massefski, Walter Pentelute, Bradley L Buchwald, Stephen L |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Rojas, Anthony J Wolfe, Justin M Dhanjee, Heemal H Buslov, Ivan Truex, Nicholas L Liu, Richard Y Massefski, Walter Pentelute, Bradley L Buchwald, Stephen L |
| author_sort | Rojas, Anthony J |
| collection | MIT |
| description | <jats:p>Peptides bearing palladium oxidative addition complexes can be synthesized from the parent aryl halide containing substrates and react with thiol functional groups of small molecules, peptides, and proteins at low micromolar concentrations.</jats:p> |
| first_indexed | 2024-09-23T15:39:50Z |
| format | Article |
| id | mit-1721.1/146551 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T15:39:50Z |
| publishDate | 2022 |
| publisher | Royal Society of Chemistry (RSC) |
| record_format | dspace |
| spelling | mit-1721.1/1465512023-01-27T19:51:47Z Palladium–peptide oxidative addition complexes for bioconjugation Rojas, Anthony J Wolfe, Justin M Dhanjee, Heemal H Buslov, Ivan Truex, Nicholas L Liu, Richard Y Massefski, Walter Pentelute, Bradley L Buchwald, Stephen L Massachusetts Institute of Technology. Department of Chemistry Koch Institute for Integrative Cancer Research at MIT Massachusetts Institute of Technology. Center for Environmental Health Sciences <jats:p>Peptides bearing palladium oxidative addition complexes can be synthesized from the parent aryl halide containing substrates and react with thiol functional groups of small molecules, peptides, and proteins at low micromolar concentrations.</jats:p> 2022-11-18T19:33:46Z 2022-11-18T19:33:46Z 2022-10-19 2022-11-18T19:28:48Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/146551 Rojas, Anthony J, Wolfe, Justin M, Dhanjee, Heemal H, Buslov, Ivan, Truex, Nicholas L et al. 2022. "Palladium–peptide oxidative addition complexes for bioconjugation." Chemical Science, 13 (40). en 10.1039/d2sc04074c Chemical Science Creative Commons Attribution NonCommercial License 3.0 https://creativecommons.org/licenses/by-nc/3.0/ application/pdf Royal Society of Chemistry (RSC) Royal Society of Chemistry (RSC) |
| spellingShingle | Rojas, Anthony J Wolfe, Justin M Dhanjee, Heemal H Buslov, Ivan Truex, Nicholas L Liu, Richard Y Massefski, Walter Pentelute, Bradley L Buchwald, Stephen L Palladium–peptide oxidative addition complexes for bioconjugation |
| title | Palladium–peptide oxidative addition complexes for bioconjugation |
| title_full | Palladium–peptide oxidative addition complexes for bioconjugation |
| title_fullStr | Palladium–peptide oxidative addition complexes for bioconjugation |
| title_full_unstemmed | Palladium–peptide oxidative addition complexes for bioconjugation |
| title_short | Palladium–peptide oxidative addition complexes for bioconjugation |
| title_sort | palladium peptide oxidative addition complexes for bioconjugation |
| url | https://hdl.handle.net/1721.1/146551 |
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