Division of labor between the pore-1 loops of the D1 and D2 AAA+ rings coordinates substrate selectivity of the ClpAP protease

ClpAP, an ATP-dependent protease consisting of ClpA, a double-ring hexameric unfoldase of the ATPases associated with diverse cellular activities superfamily, and the ClpP peptidase, degrades damaged and unneeded proteins to support cellular proteostasis. ClpA recognizes many protein substrates dire...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zuromski, Kristin L, Kim, Sora, Sauer, Robert T, Baker, Tania A
Άλλοι συγγραφείς: Massachusetts Institute of Technology. Department of Biology
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Elsevier BV 2022
Διαθέσιμο Online:https://hdl.handle.net/1721.1/146734