AAA+ protease-adaptor structures reveal altered conformations and ring specialization

<jats:title>Abstract</jats:title><jats:p>ClpAP, a two-ring AAA+ protease, degrades N-end-rule proteins bound by the ClpS adaptor. Here we present high-resolution cryo-EM structures of <jats:italic>Escherichia coli</jats:italic> ClpAPS complexes, showing how ClpA pore lo...

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Autori principali: Kim, Sora, Fei, Xue, Sauer, Robert T, Baker, Tania A
Altri autori: Massachusetts Institute of Technology. Department of Biology
Natura: Articolo
Lingua:English
Pubblicazione: Springer Science and Business Media LLC 2022
Accesso online:https://hdl.handle.net/1721.1/146735