Cell size is a determinant of stem cell potential during aging

<jats:p>Small cell size preserves the function of hematopoietic stem cells (HSCs); HSC enlargement during aging causes their dysfunction.</jats:p>

Bibliographic Details
Main Authors: Lengefeld, Jette, Cheng, Chia-Wei, Maretich, Pema, Blair, Marguerite, Hagen, Hannah, McReynolds, Melanie R, Sullivan, Emily, Majors, Kyra, Roberts, Christina, Kang, Joon Ho, Steiner, Joachim D, Miettinen, Teemu P, Manalis, Scott R, Antebi, Adam, Morrison, Sean J, Lees, Jacqueline A, Boyer, Laurie A, Yilmaz, Ömer H, Amon, Angelika
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022
Online Access:https://hdl.handle.net/1721.1/146768
Description
Summary:<jats:p>Small cell size preserves the function of hematopoietic stem cells (HSCs); HSC enlargement during aging causes their dysfunction.</jats:p>