Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein
Pyruvate formate-lyase (PFL) is a glycyl radical enzyme (GRE) that converts pyruvate and coenzyme A into acetyl-CoA and formate in a reaction that is crucial to the primary metabolism of many anaerobic bacteria. The glycyl radical cofactor, which is posttranslationally installed by a radical S-adeno...
Main Authors: | Andorfer, Mary C, Backman, Lindsey RF, Li, Phoebe L, Ulrich, Emily C, Drennan, Catherine L |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2022
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Online Access: | https://hdl.handle.net/1721.1/146790 |
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