Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy

Microenvironmental IL-6 inhibits anti-cancer immune responses generated by cytotoxic chemotherapy

Cytotoxic chemotherapeutics primarily function through DNA damage-induced tumor cell apoptosis, although the inflammation provoked by these agents can stimulate anti-cancer immune responses. The mechanisms that control these distinct effects and limit immunogenic responses to DNA-damage mediated cel...

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Bibliographic Details
Main Authors: Bent, Eric H, Millán-Barea, Luis R, Zhuang, Iris, Goulet, Daniel R, Fröse, Julia, Hemann, Michael T
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2022
Online Access:https://hdl.handle.net/1721.1/146807

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