Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium

Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell–derived alveolar epithelium

Type 2 alveolar epithelial cells (AT2s), facultative progenitor cells of the lung alveolus, play a vital role in the biology of the distal lung. In vitro model systems that incorporate human cells, recapitulate the biology of primary AT2s, and interface with the outside environment could serve as us...

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Bibliographic Details
Main Authors: Abo, Kristine M, Sainz de Aja, Julio, Lindstrom-Vautrin, Jonathan, Alysandratos, Konstantinos-Dionysios, Richards, Alexsia, Garcia-de-Alba, Carolina, Huang, Jessie, Hix, Olivia T, Werder, Rhiannon B, Bullitt, Esther, Hinds, Anne, Falconer, Isaac, Villacorta-Martin, Carlos, Jaenisch, Rudolf, Kim, Carla F, Kotton, Darrell N, Wilson, Andrew A
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022
Online Access:https://hdl.handle.net/1721.1/146847

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