A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers

A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers

<jats:p>Metazoan proteomes contain many paralogous proteins that have evolved distinct functions. The Ena/VASP family of actin regulators consists of three members that share an EVH1 interaction domain with a 100 % conserved binding site. A proteome-wide screen revealed photoreceptor cilium ac...

Full description

Bibliographic Details
Main Authors: Hwang, Theresa, Parker, Sara S, Hill, Samantha M, Ilunga, Meucci W, Grant, Robert A, Mouneimne, Ghassan, Keating, Amy E
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd 2022
Online Access:https://hdl.handle.net/1721.1/146849

Similar Items

Similar Items