Evolution towards Virulence in a Burkholderia Two-Component System
<jats:p> Infections caused by members of the <jats:named-content content-type="genus-species">Burkholderia cepacia</jats:named-content> complex (BCC) are a serious concern for patients with cystic fibrosis (CF) as these bacteria are...
Main Authors: | , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2022
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Online Access: | https://hdl.handle.net/1721.1/146863 |
Summary: | <jats:p>
Infections caused by members of the
<jats:named-content content-type="genus-species">Burkholderia cepacia</jats:named-content>
complex (BCC) are a serious concern for patients with cystic fibrosis (CF) as these bacteria are often resistant to many antibiotics. During long-term infection of CF patients with BCC, mutations in genes encoding the FixLJ system often become prevalent, suggesting that these changes may benefit the bacteria during infection.
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