A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP
<jats:p> Drug-resistant Gram-negative bacteria have become the major problem driving the antimicrobial resistance crisis. Searching outside the overmined actinomycetes, we focused on <jats:italic>Photorhabdus</jats:italic> , gut symbionts of e...
| Main Authors: | , , , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2022
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| Online Access: | https://hdl.handle.net/1721.1/146865 |
| _version_ | 1826217566192795648 |
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| author | Shahsavari, Negar Wang, Boyuan Imai, Yu Mori, Miho Son, Sangkeun Liang, Libang Böhringer, Nils Manuse, Sylvie Gates, Michael F Morrissette, Madeleine Corsetti, Rachel Espinoza, Josh L Dupont, Chris L Laub, Michael T Lewis, Kim |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Shahsavari, Negar Wang, Boyuan Imai, Yu Mori, Miho Son, Sangkeun Liang, Libang Böhringer, Nils Manuse, Sylvie Gates, Michael F Morrissette, Madeleine Corsetti, Rachel Espinoza, Josh L Dupont, Chris L Laub, Michael T Lewis, Kim |
| author_sort | Shahsavari, Negar |
| collection | MIT |
| description | <jats:p>
Drug-resistant Gram-negative bacteria have become the major problem driving the antimicrobial resistance crisis. Searching outside the overmined actinomycetes, we focused on
<jats:italic>Photorhabdus</jats:italic>
, gut symbionts of enthomopathogenic nematodes that carry up to 40 biosynthetic gene clusters coding for secondary metabolites.
</jats:p> |
| first_indexed | 2024-09-23T17:05:42Z |
| format | Article |
| id | mit-1721.1/146865 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T17:05:42Z |
| publishDate | 2022 |
| publisher | American Society for Microbiology |
| record_format | dspace |
| spelling | mit-1721.1/1468652022-12-14T03:00:32Z A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP Shahsavari, Negar Wang, Boyuan Imai, Yu Mori, Miho Son, Sangkeun Liang, Libang Böhringer, Nils Manuse, Sylvie Gates, Michael F Morrissette, Madeleine Corsetti, Rachel Espinoza, Josh L Dupont, Chris L Laub, Michael T Lewis, Kim Massachusetts Institute of Technology. Department of Biology <jats:p> Drug-resistant Gram-negative bacteria have become the major problem driving the antimicrobial resistance crisis. Searching outside the overmined actinomycetes, we focused on <jats:italic>Photorhabdus</jats:italic> , gut symbionts of enthomopathogenic nematodes that carry up to 40 biosynthetic gene clusters coding for secondary metabolites. </jats:p> 2022-12-13T18:50:01Z 2022-12-13T18:50:01Z 2022 2022-12-13T18:38:54Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/146865 Shahsavari, Negar, Wang, Boyuan, Imai, Yu, Mori, Miho, Son, Sangkeun et al. 2022. "A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP." mBio, 13 (3). en 10.1128/MBIO.00700-22 mBio Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf American Society for Microbiology American Society for Microbiology |
| spellingShingle | Shahsavari, Negar Wang, Boyuan Imai, Yu Mori, Miho Son, Sangkeun Liang, Libang Böhringer, Nils Manuse, Sylvie Gates, Michael F Morrissette, Madeleine Corsetti, Rachel Espinoza, Josh L Dupont, Chris L Laub, Michael T Lewis, Kim A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP |
| title | A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP |
| title_full | A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP |
| title_fullStr | A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP |
| title_full_unstemmed | A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP |
| title_short | A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP |
| title_sort | silent operon of photorhabdus luminescens encodes a prodrug mimic of gtp |
| url | https://hdl.handle.net/1721.1/146865 |
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