Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles
<jats:title>Abstract</jats:title><jats:p>Engineered signaling networks can impart cells with new functionalities useful for directing differentiation and actuating cellular therapies. For such applications, the engineered networks must be tunable, precisely regulate target gene exp...
Main Authors: | Jones, Ross D, Qian, Yili, Ilia, Katherine, Wang, Benjamin, Laub, Michael T, Del Vecchio, Domitilla, Weiss, Ron |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2022
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Online Access: | https://hdl.handle.net/1721.1/146867 |
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