Screening the Toxoplasma kinome with high-throughput tagging identifies a regulator of invasion and egress
Protein kinases regulate fundamental aspects of eukaryotic cell biology, making them attractive chemotherapeutic targets in parasites like Plasmodium spp. and Toxoplasma gondii. To systematically examine the parasite kinome, we developed a high-throughput tagging (HiT) strategy to endogenously label...
Main Authors: | Smith, Tyler A, Lopez-Perez, Gabriella S, Herneisen, Alice L, Shortt, Emily, Lourido, Sebastian |
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Outros autores: | Massachusetts Institute of Technology. Department of Biology |
Formato: | Artigo |
Idioma: | English |
Publicado: |
Springer Science and Business Media LLC
2022
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Acceso en liña: | https://hdl.handle.net/1721.1/146902 |
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