SHIMS 3.0: Highly efficient single-haplotype iterative mapping and sequencing using ultra-long nanopore reads

<jats:p>The reference sequence of structurally complex regions can only be obtained through a highly accurate clone-based approach that we call Single-Haplotype Iterative Mapping and Sequencing (SHIMS). In recent years, improvements to SHIMS have reduced the cost and time required by two order...

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Bibliographic Details
Main Authors: Bellott, Daniel W, Cho, Ting-Jan, Jackson, Emily K, Skaletsky, Helen, Hughes, Jennifer F, Page, David C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023
Online Access:https://hdl.handle.net/1721.1/146948