Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair
<jats:p>Bacterial cell death is a poorly understood process. The generation of reactive oxygen species (ROS) is an apparently common response to challenges by a wide variety of lethal stresses, including bactericidal antibiotics.</jats:p>
| Main Authors: | , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2023
|
| Online Access: | https://hdl.handle.net/1721.1/147002 |
| _version_ | 1826194676071268352 |
|---|---|
| author | Gruber, Charley C Babu, Vignesh MP Livingston, Kamren Joisher, Heer Walker, Graham C |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Gruber, Charley C Babu, Vignesh MP Livingston, Kamren Joisher, Heer Walker, Graham C |
| author_sort | Gruber, Charley C |
| collection | MIT |
| description | <jats:p>Bacterial cell death is a poorly understood process. The generation of reactive oxygen species (ROS) is an apparently common response to challenges by a wide variety of lethal stresses, including bactericidal antibiotics.</jats:p> |
| first_indexed | 2024-09-23T09:59:53Z |
| format | Article |
| id | mit-1721.1/147002 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T09:59:53Z |
| publishDate | 2023 |
| publisher | American Society for Microbiology |
| record_format | dspace |
| spelling | mit-1721.1/1470022023-01-07T03:37:35Z Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair Gruber, Charley C Babu, Vignesh MP Livingston, Kamren Joisher, Heer Walker, Graham C Massachusetts Institute of Technology. Department of Biology <jats:p>Bacterial cell death is a poorly understood process. The generation of reactive oxygen species (ROS) is an apparently common response to challenges by a wide variety of lethal stresses, including bactericidal antibiotics.</jats:p> 2023-01-06T18:19:06Z 2023-01-06T18:19:06Z 2022 2023-01-06T18:10:49Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/147002 Gruber, Charley C, Babu, Vignesh MP, Livingston, Kamren, Joisher, Heer and Walker, Graham C. 2022. "Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair." mBio, 13 (1). en 10.1128/MBIO.03756-21 mBio Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf American Society for Microbiology American Society for Microbiology |
| spellingShingle | Gruber, Charley C Babu, Vignesh MP Livingston, Kamren Joisher, Heer Walker, Graham C Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair |
| title | Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair |
| title_full | Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair |
| title_fullStr | Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair |
| title_full_unstemmed | Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair |
| title_short | Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair |
| title_sort | degradation of the escherichia coli essential proteins dapb and dxr results in oxidative stress which contributes to lethality through incomplete base excision repair |
| url | https://hdl.handle.net/1721.1/147002 |
| work_keys_str_mv | AT grubercharleyc degradationoftheescherichiacoliessentialproteinsdapbanddxrresultsinoxidativestresswhichcontributestolethalitythroughincompletebaseexcisionrepair AT babuvigneshmp degradationoftheescherichiacoliessentialproteinsdapbanddxrresultsinoxidativestresswhichcontributestolethalitythroughincompletebaseexcisionrepair AT livingstonkamren degradationoftheescherichiacoliessentialproteinsdapbanddxrresultsinoxidativestresswhichcontributestolethalitythroughincompletebaseexcisionrepair AT joisherheer degradationoftheescherichiacoliessentialproteinsdapbanddxrresultsinoxidativestresswhichcontributestolethalitythroughincompletebaseexcisionrepair AT walkergrahamc degradationoftheescherichiacoliessentialproteinsdapbanddxrresultsinoxidativestresswhichcontributestolethalitythroughincompletebaseexcisionrepair |