Trauma-induced heme release increases susceptibility to bacterial infection
Infection is a common complication of major trauma that causes significantly increased morbidity and mortality. The mechanisms, however, linking tissue injury to increased susceptibility to infection remain poorly understood. To study this relationship, we present a potentially novel murine model in...
Main Authors: | Lee, Ghee Rye, Gallo, David, Alves de Souza, Rodrigo W, Tiwari-Heckler, Shilpa, Csizmadia, Eva, Harbison, James D, Shankar, Sidharth, Banner-Goodspeed, Valerie, Yaffe, Michael B, Longhi, Maria Serena, Hauser, Carl J, Otterbein, Leo E |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2023
|
Online Access: | https://hdl.handle.net/1721.1/147024 |
Similar Items
-
Circulating Factors in Trauma Plasma Activate Specific Human Immune Cell Subsets
by: Cahill, Laura A, et al.
Published: (2021) -
Evidence for heme oxygenase activity in a heme peroxidase.
by: Badyal, S, et al.
Published: (2009) -
Molecular hijacking of siroheme for the synthesis of heme and d1 heme.
by: Bali, S, et al.
Published: (2011) -
Proton delivery to ferryl heme in a heme peroxidase: enzymatic use of the Grotthuss mechanism.
by: Efimov, I, et al.
Published: (2011) -
Identification of an intestinal heme transporter.
by: Shayeghi, M, et al.
Published: (2005)