Immunogenic cell stress and injury versus immunogenic cell death: implications for improving cancer treatment with immune checkpoint blockade
Inducing immunogenic tumor cell death to stimulate the response to immune checkpoint blockade has not yet been effectively translated into clinical practice. We recently discovered that stressed/injured but still viable tumor cells are critical for T-cell priming and substantially improve responses...
Main Authors: | Sriram, Ganapathy, Emmons, Tiffany R, Milling, Lauren E, Irvine, Darrell J, Yaffe, Michael B |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Informa UK Limited
2023
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Online Access: | https://hdl.handle.net/1721.1/147026 |
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