Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis
Little is known about how interactions of diet, intestinal stem cells (ISCs), and immune cells affect early-stage intestinal tumorigenesis. We show that a high-fat diet (HFD) reduces the expression of the major histocompatibility complex class II (MHC class II) genes in intestinal epithelial cells,...
Main Author: | Yilmaz, Omer |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2023
|
Online Access: | https://hdl.handle.net/1721.1/147038 |
Similar Items
-
Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis.
by: Christoph Thelemann, et al.
Published: (2014-01-01) -
Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity
by: Emily M. Eshleman, et al.
Published: (2023-02-01) -
Intestinal epithelial cell autophagy deficiency suppresses inflammation-associated colon tumorigenesis
by: Hao Liu, et al.
Published: (2022-06-01) -
Epithelial MHC class II sub-region expression in autoimmunity.
by: Todd, I, et al.
Published: (1986) -
PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis
by: Sakthianandeswaren, A, et al.
Published: (2011)