Spatially organized multicellular immune hubs in human colorectal cancer

Immune responses to cancer are highly variable, with mismatch repair-deficient (MMRd) tumors exhibiting more anti-tumor immunity than mismatch repair-proficient (MMRp) tumors. To understand the rules governing these varied responses, we transcriptionally profiled 371,223 cells from colorectal tumors...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir: Regev, Aviv
Rannpháirtithe: Massachusetts Institute of Technology. Department of Biology
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Elsevier BV 2023
Rochtain ar líne:https://hdl.handle.net/1721.1/147100