Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences

Nanopore Sequencing for Detection and Characterization of Phosphorothioate Modifications in Native DNA Sequences

<jats:p>Bacterial DNA is subject to various modifications involved in gene regulation and defense against bacteriophage attacks. Phosphorothioate (PT) modifications are protective modifications in which the non-bridging oxygen in the DNA phosphate backbone is replaced with a sulfur atom. Here,...

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Bibliographic Details
Main Authors: Wadley, Taylor, Moon, Sun Hee, DeMott, Michael S, Wanchai, Visanu, Huang, En, Dedon, Peter C, Boysen, Gunnar, Nookaew, Intawat
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Frontiers Media SA 2023
Online Access:https://hdl.handle.net/1721.1/147795

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