Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m6A consensus sequences

Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing m6A consensus sequences

Extracellular vesicles (EVs) are capable of transferring cargo from donor to recipient cells, but precisely how cargo content is regulated for export is mostly unknown. For miRNA cargo, we previously showed that when compared to isogenic colorectal cancer (CRC) cells expressing wild-type KRAS, a dis...

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Bibliographic Details
Main Authors: Abner, Jessica J, Franklin, Jeffrey L, Clement, Margaret A, Hinger, Scott A, Allen, Ryan M, Liu, Xiao, Kellner, Stefanie, Wu, Junzhou, Karijolich, John, Liu, Qi, Vickers, Kasey C, Dedon, Peter, Weaver, Alissa M, Coffey, Robert J, Patton, James G
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2023
Online Access:https://hdl.handle.net/1721.1/147799

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