Cell environment shapes TDP-43 function with implications in neuronal and muscle disease

<jats:title>Abstract</jats:title><jats:p>TDP-43 (TAR DNA-binding protein 43) aggregation and redistribution are recognised as a hallmark of amyotrophic lateral sclerosis and frontotemporal dementia. As TDP-43 inclusions have recently been described in the muscle of inclusion body m...

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Bibliographic Details
Main Author: Fraenkel, Ernest
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/147815