Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging

Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging

<jats:p> Animal genomes are folded into loops and topologically associating domains (TADs) by CTCF and loop-extruding cohesins, but the live dynamics of loop formation and stability remain unknown. Here, we directly visualized chromatin looping at the <jats:italic&...

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Bibliographic Details
Main Authors: Gabriele, Michele, Brandão, Hugo B, Grosse-Holz, Simon, Jha, Asmita, Dailey, Gina M, Cattoglio, Claudia, Hsieh, Tsung-Han S, Mirny, Leonid, Zechner, Christoph, Hansen, Anders S
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023
Online Access:https://hdl.handle.net/1721.1/147831

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