In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation

In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation

© 2020 The American Society of Gene and Cell Therapy Synthetic mRNA therapeutics have the potential to revolutionize healthcare, as they enable patients to produce therapeutic proteins inside their own bodies. However, convenient methods that allow external control over the timing and magnitude of p...

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Bibliographic Details
Main Authors: Mc Cafferty, Sean, De Temmerman, Joyca, Kitada, Tasuku, Becraft, Jacob R, Weiss, Ron, Irvine, Darrell J, Devreese, Mathias, De Baere, Siegrid, Combes, Francis, Sanders, Niek N
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2023
Online Access:https://hdl.handle.net/1721.1/147837

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