Synthetic extracellular matrices and astrocytes provide a supportive microenvironment for the cultivation and investigation of primary pediatric gliomas

Synthetic extracellular matrices and astrocytes provide a supportive microenvironment for the cultivation and investigation of primary pediatric gliomas

Abstract Background. Pediatric gliomas comprise a diverse set of brain tumor entities that have substantial long-term ramifications for patient survival and quality of life. However, the study of these tumors is currently limited due to a lack of authentic models. Additionally, many aspects of pe...

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Bibliographic Details
Main Authors: Rota, Christopher M, Brown, Alexander T, Addleson, Emily, Ives, Clara, Trumper, Ella, Pelton, Kristine, Teh, Wei Pin, Schniederjan, Matthew J, Castellino, Robert Craig, Buhrlage, Sara, Lauffenburger, Douglas A, Ligon, Keith L, Griffith, Linda G, Segal, Rosalind A
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Oxford University Press (OUP) 2023
Online Access:https://hdl.handle.net/1721.1/147854

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