The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia

The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia

<jats:p>We showed that persistent SARS-CoV-2 RNAemia is an independent predictor of severe COVID-19. We observed that SARS-CoV-2-targeted antibody maturation, specifically Fc-effector functions rather than neutralization, was strongly linked with the ability to rapidly clear viremia.</jats:...

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Bibliographic Details
Main Authors: Wang, Chuangqi, Li, Yijia, Kaplonek, Paulina, Gentili, Matteo, Fischinger, Stephanie, Bowman, Kathryn A, Sade-Feldman, Moshe, Kays, Kyle R, Regan, James, Flynn, James P, Goldberg, Marcia B, Hacohen, Nir, Filbin, Michael R, Lauffenburger, Douglas A, Alter, Galit, Li, Jonathan Z
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Society for Microbiology 2023
Online Access:https://hdl.handle.net/1721.1/147856

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