Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity
<jats:p>Recent data indicates improved immunity to SARS-CoV-2 in individuals who experience a combination of two mRNA vaccine doses and infection, “hybrid immunity,” compared to individuals who receive vaccination or experience infection alone. While previous infection accelerates the vaccine-...
| Main Authors: | , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
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American Society for Microbiology
2023
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| Online Access: | https://hdl.handle.net/1721.1/147858 |
| _version_ | 1826215543101718528 |
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| author | Bowman, Kathryn A Stein, Daniel Shin, Sally Ferbas, Kathie G Tobin, Nicole H Mann, Colin Fischinger, Stephanie Ollmann Saphire, Erica Lauffenburger, Douglas Rimoin, Anne W Aldrovandi, Grace Alter, Galit |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Bowman, Kathryn A Stein, Daniel Shin, Sally Ferbas, Kathie G Tobin, Nicole H Mann, Colin Fischinger, Stephanie Ollmann Saphire, Erica Lauffenburger, Douglas Rimoin, Anne W Aldrovandi, Grace Alter, Galit |
| author_sort | Bowman, Kathryn A |
| collection | MIT |
| description | <jats:p>Recent data indicates improved immunity to SARS-CoV-2 in individuals who experience a combination of two mRNA vaccine doses and infection, “hybrid immunity,” compared to individuals who receive vaccination or experience infection alone. While previous infection accelerates the vaccine-induced immune response following the first dose of mRNA vaccination, subsequent doses demonstrate negligible increases in antibody titers or T cell immunity.</jats:p> |
| first_indexed | 2024-09-23T16:34:20Z |
| format | Article |
| id | mit-1721.1/147858 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T16:34:20Z |
| publishDate | 2023 |
| publisher | American Society for Microbiology |
| record_format | dspace |
| spelling | mit-1721.1/1478582023-02-04T03:02:25Z Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity Bowman, Kathryn A Stein, Daniel Shin, Sally Ferbas, Kathie G Tobin, Nicole H Mann, Colin Fischinger, Stephanie Ollmann Saphire, Erica Lauffenburger, Douglas Rimoin, Anne W Aldrovandi, Grace Alter, Galit Massachusetts Institute of Technology. Department of Biological Engineering <jats:p>Recent data indicates improved immunity to SARS-CoV-2 in individuals who experience a combination of two mRNA vaccine doses and infection, “hybrid immunity,” compared to individuals who receive vaccination or experience infection alone. While previous infection accelerates the vaccine-induced immune response following the first dose of mRNA vaccination, subsequent doses demonstrate negligible increases in antibody titers or T cell immunity.</jats:p> 2023-02-03T16:58:26Z 2023-02-03T16:58:26Z 2022 2023-02-03T16:55:06Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/147858 Bowman, Kathryn A, Stein, Daniel, Shin, Sally, Ferbas, Kathie G, Tobin, Nicole H et al. 2022. "Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity." mBio, 13 (5). en 10.1128/MBIO.01647-22 mBio Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf American Society for Microbiology mBio |
| spellingShingle | Bowman, Kathryn A Stein, Daniel Shin, Sally Ferbas, Kathie G Tobin, Nicole H Mann, Colin Fischinger, Stephanie Ollmann Saphire, Erica Lauffenburger, Douglas Rimoin, Anne W Aldrovandi, Grace Alter, Galit Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity |
| title | Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity |
| title_full | Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity |
| title_fullStr | Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity |
| title_full_unstemmed | Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity |
| title_short | Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity |
| title_sort | hybrid immunity shifts the fc effector quality of sars cov 2 mrna vaccine induced immunity |
| url | https://hdl.handle.net/1721.1/147858 |
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