Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain

Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain

The Omicron variant features enhanced transmissibility and antibody escape. Here, we describe the Omicron receptor-binding domain (RBD) mutational landscape using amino acid interaction (AAI) networks, which are well suited for interrogating constellations of mutations that function in an epistatic...

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Bibliographic Details
Main Authors: Miller, Nathaniel L, Clark, Thomas, Raman, Rahul, Sasisekharan, Ram
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2023
Online Access:https://hdl.handle.net/1721.1/147927

Internet

https://hdl.handle.net/1721.1/147927

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