Nα-Methylation of arginine: Implications for cell-penetrating peptides
The field of cell-penetrating peptides is dominated by the use of oligomers of arginine residues. Octanol-water partitioning in the presence of an anionic lipid is a validated proxy for cell-penetrative efficacy. Here, we add one, two, or three N-methyl groups to Ac-Arg-NH2 and examine the effects o...
Main Authors: | Calabretta, Lindsey O, Yang, Jinyi, Raines, Ronald T |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | English |
Published: |
Wiley
2023
|
Online Access: | https://hdl.handle.net/1721.1/148050 |
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