7.346 DNA Wars: How the Cell Strikes Back to Avoid Disease after Attacks on DNA, Fall 2013
A never-ending molecular war takes place in the nucleus of your cells, with DNA damage occurring at a rate of over 20,000 lesions per cell per day. Where does this damage come from, and what are its consequences? What are the differences in the molecular blueprint between individuals who can sustain...
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| Format: | Learning Object |
| Language: | en-US |
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2023
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| Online Access: | https://hdl.handle.net/1721.1/148318 |
| _version_ | 1826204814855372800 |
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| author | Jordan, Jennifer Nagel, Zachary |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Jordan, Jennifer Nagel, Zachary |
| author_sort | Jordan, Jennifer |
| collection | MIT |
| description | A never-ending molecular war takes place in the nucleus of your cells, with DNA damage occurring at a rate of over 20,000 lesions per cell per day. Where does this damage come from, and what are its consequences? What are the differences in the molecular blueprint between individuals who can sustain attacks on DNA and remain healthy compared to those who become sick? This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. |
| first_indexed | 2024-09-23T13:01:50Z |
| format | Learning Object |
| id | mit-1721.1/148318 |
| institution | Massachusetts Institute of Technology |
| language | en-US |
| last_indexed | 2025-03-10T11:03:48Z |
| publishDate | 2023 |
| record_format | dspace |
| spelling | mit-1721.1/1483182025-02-26T21:25:46Z 7.346 DNA Wars: How the Cell Strikes Back to Avoid Disease after Attacks on DNA, Fall 2013 DNA Wars: How the Cell Strikes Back to Avoid Disease after Attacks on DNA Jordan, Jennifer Nagel, Zachary Massachusetts Institute of Technology. Department of Biology DNA damage DNA repair mismatch repair direct reversal nucleotide excision repair base excision repair double strand break repair nuclear DNA damage mitochondrial DNA damage Alkylating agents replication errors mutations epigenetics base excision repair Werner helicase activity 260801 A never-ending molecular war takes place in the nucleus of your cells, with DNA damage occurring at a rate of over 20,000 lesions per cell per day. Where does this damage come from, and what are its consequences? What are the differences in the molecular blueprint between individuals who can sustain attacks on DNA and remain healthy compared to those who become sick? This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. 2023-03-06T16:41:53Z 2023-03-06T16:41:53Z 2013-12 2023-03-06T16:41:59Z Learning Object 7.346-Fall2013 7.346 IMSCP-MD5-47fedbe1663a80b3790271efb1839d4c https://hdl.handle.net/1721.1/148318 en-US This site (c) Massachusetts Institute of Technology 2023. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions. 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| spellingShingle | DNA damage DNA repair mismatch repair direct reversal nucleotide excision repair base excision repair double strand break repair nuclear DNA damage mitochondrial DNA damage Alkylating agents replication errors mutations epigenetics base excision repair Werner helicase activity 260801 Jordan, Jennifer Nagel, Zachary 7.346 DNA Wars: How the Cell Strikes Back to Avoid Disease after Attacks on DNA, Fall 2013 |
| title | 7.346 DNA Wars: How the Cell Strikes Back to Avoid Disease after Attacks on DNA, Fall 2013 |
| title_full | 7.346 DNA Wars: How the Cell Strikes Back to Avoid Disease after Attacks on DNA, Fall 2013 |
| title_fullStr | 7.346 DNA Wars: How the Cell Strikes Back to Avoid Disease after Attacks on DNA, Fall 2013 |
| title_full_unstemmed | 7.346 DNA Wars: How the Cell Strikes Back to Avoid Disease after Attacks on DNA, Fall 2013 |
| title_short | 7.346 DNA Wars: How the Cell Strikes Back to Avoid Disease after Attacks on DNA, Fall 2013 |
| title_sort | 7 346 dna wars how the cell strikes back to avoid disease after attacks on dna fall 2013 |
| topic | DNA damage DNA repair mismatch repair direct reversal nucleotide excision repair base excision repair double strand break repair nuclear DNA damage mitochondrial DNA damage Alkylating agents replication errors mutations epigenetics base excision repair Werner helicase activity 260801 |
| url | https://hdl.handle.net/1721.1/148318 |
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