7.345 Using Simple Organisms to Model Human Diseases, Spring 2013

How do scientists discover the basic biology underlying human diseases? Simple organisms such as baker’s yeast, nematodes, fruit flies, zebrafish, mice and rats have allowed biologists to investigate disease at multiple levels, from molecules to behavior. In this course students will learn...

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Main Author: Harris, Katie
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Learning Object
Language:en-US
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/1721.1/148321
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author Harris, Katie
author2 Massachusetts Institute of Technology. Department of Biology
author_facet Massachusetts Institute of Technology. Department of Biology
Harris, Katie
author_sort Harris, Katie
collection MIT
description How do scientists discover the basic biology underlying human diseases? Simple organisms such as baker’s yeast, nematodes, fruit flies, zebrafish, mice and rats have allowed biologists to investigate disease at multiple levels, from molecules to behavior. In this course students will learn strategies of disease modeling by critically reading and discussing primary research articles. We will explore current models of neurodegenerative diseases such as Parkinson’s disease, childhood genetic diseases such as Fragile X syndrome, as well as models of deafness and wound healing. Our goal will be to understand the strategies biologists use to build appropriate models of human disease and to appreciate both the power and limitations of using simple organisms to analyze human disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
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spelling mit-1721.1/1483212025-02-26T21:25:35Z 7.345 Using Simple Organisms to Model Human Diseases, Spring 2013 Using Simple Organisms to Model Human Diseases Harris, Katie Massachusetts Institute of Technology. Department of Biology human disease yeast nematodes fruit flies zebrafish mice rats Parkinson's disease Fragile X syndrome deafness wound healing experimental organisms genetic models Huntington's disease Drosophila melanogaster 260503 How do scientists discover the basic biology underlying human diseases? Simple organisms such as baker’s yeast, nematodes, fruit flies, zebrafish, mice and rats have allowed biologists to investigate disease at multiple levels, from molecules to behavior. In this course students will learn strategies of disease modeling by critically reading and discussing primary research articles. We will explore current models of neurodegenerative diseases such as Parkinson’s disease, childhood genetic diseases such as Fragile X syndrome, as well as models of deafness and wound healing. Our goal will be to understand the strategies biologists use to build appropriate models of human disease and to appreciate both the power and limitations of using simple organisms to analyze human disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. 2023-03-06T16:45:33Z 2023-03-06T16:45:33Z 2013-06 2023-03-06T16:45:39Z Learning Object 7.345-Spring2013 7.345 IMSCP-MD5-9809f48037f7e74434387a828aa6c829 https://hdl.handle.net/1721.1/148321 en-US This site (c) Massachusetts Institute of Technology 2023. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions. Attribution-NonCommercial-ShareAlike 3.0 Unported http://creativecommons.org/licenses/by-nc-sa/3.0/ text/plain text/html image/jpeg text/html image/jpeg text/html text/html text/html text/html application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/html image/png image/png image/png image/png image/gif image/png image/png image/png image/jpeg image/gif image/png image/png image/png image/gif image/png image/png image/png image/png image/png image/png image/gif image/png image/png image/gif image/gif image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/jpeg image/gif image/png image/jpeg image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/png image/png image/jpeg image/gif image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/png image/gif application/octet-stream image/gif image/gif image/png image/gif image/gif image/gif image/png image/png application/octet-stream image/gif image/gif image/gif image/gif image/png image/gif image/gif application/octet-stream image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png application/rdf+xml; charset=utf-8 text/html image/png image/png image/jpeg image/png image/png image/png image/png image/png text/html text/html Spring 2013
spellingShingle human disease
yeast
nematodes
fruit flies
zebrafish
mice
rats
Parkinson's disease
Fragile X syndrome
deafness
wound healing
experimental organisms
genetic models
Huntington's disease
Drosophila melanogaster
260503
Harris, Katie
7.345 Using Simple Organisms to Model Human Diseases, Spring 2013
title 7.345 Using Simple Organisms to Model Human Diseases, Spring 2013
title_full 7.345 Using Simple Organisms to Model Human Diseases, Spring 2013
title_fullStr 7.345 Using Simple Organisms to Model Human Diseases, Spring 2013
title_full_unstemmed 7.345 Using Simple Organisms to Model Human Diseases, Spring 2013
title_short 7.345 Using Simple Organisms to Model Human Diseases, Spring 2013
title_sort 7 345 using simple organisms to model human diseases spring 2013
topic human disease
yeast
nematodes
fruit flies
zebrafish
mice
rats
Parkinson's disease
Fragile X syndrome
deafness
wound healing
experimental organisms
genetic models
Huntington's disease
Drosophila melanogaster
260503
url https://hdl.handle.net/1721.1/148321
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