7.345 The Science of Sperm, Fall 2014
Sperm are tiny, haploid cells with a supremely important job: They deliver the paternal genome to the egg, helping create a zygote that develops into a new individual. For a human male, however, only a small fraction of the sperm produced will ever fertilize an egg. Sperm thus experience intense sel...
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| Language: | en-US |
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2023
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| Online Access: | https://hdl.handle.net/1721.1/148324 |
| _version_ | 1811080106979885056 |
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| author | Lesch, Bluma (Bibi) George, Renee |
| author_facet | Lesch, Bluma (Bibi) George, Renee |
| author_sort | Lesch, Bluma (Bibi) |
| collection | MIT |
| description | Sperm are tiny, haploid cells with a supremely important job: They deliver the paternal genome to the egg, helping create a zygote that develops into a new individual. For a human male, however, only a small fraction of the sperm produced will ever fertilize an egg. Sperm thus experience intense selective pressure: They must compete against each other, navigate a foreign environment in the female reproductive tract, and interact specifically and appropriately with the surface of the egg. These selective pressures can drive extreme changes in morphology and gene function over short evolutionary time scales, resulting in amazing diversity among species. In this course, we will explore the ways in which these unique evolutionary forces contribute to incredible specializations of sperm form and function, including hook-shaped heads and multiple tails. Students will learn from the primary research literature with an emphasis on rigorously interpreting experimental data and critiquing analyses and conclusions. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. |
| first_indexed | 2024-09-23T11:25:56Z |
| id | mit-1721.1/148324 |
| institution | Massachusetts Institute of Technology |
| language | en-US |
| last_indexed | 2024-09-23T11:25:56Z |
| publishDate | 2023 |
| record_format | dspace |
| spelling | mit-1721.1/1483242023-03-07T04:00:39Z 7.345 The Science of Sperm, Fall 2014 The Science of Sperm Lesch, Bluma (Bibi) George, Renee sperm sperm biology haploid cells sperm development selective forces meiotic cell division protamines fertilization evolutionary analysis reproductive biology spermatogenesis spermatogenic cycle germline mutations FGFR2 gene germ line selection Fragile X syndrome Meiotic recombination sperm bundling Sperm Cooperation sperm competition 260404 Sperm are tiny, haploid cells with a supremely important job: They deliver the paternal genome to the egg, helping create a zygote that develops into a new individual. For a human male, however, only a small fraction of the sperm produced will ever fertilize an egg. Sperm thus experience intense selective pressure: They must compete against each other, navigate a foreign environment in the female reproductive tract, and interact specifically and appropriately with the surface of the egg. These selective pressures can drive extreme changes in morphology and gene function over short evolutionary time scales, resulting in amazing diversity among species. In this course, we will explore the ways in which these unique evolutionary forces contribute to incredible specializations of sperm form and function, including hook-shaped heads and multiple tails. Students will learn from the primary research literature with an emphasis on rigorously interpreting experimental data and critiquing analyses and conclusions. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. 2023-03-06T16:49:06Z 2023-03-06T16:49:06Z 2014-12 2023-03-06T16:49:12Z 7.345-Fall2014 7.345 IMSCP-MD5-aa347dce663e40a3f83c0692f7eaa65a https://hdl.handle.net/1721.1/148324 en-US This site (c) Massachusetts Institute of Technology 2023. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions. Attribution-NonCommercial-ShareAlike 3.0 Unported http://creativecommons.org/licenses/by-nc-sa/3.0/ text/plain text/html image/jpeg image/jpeg text/html text/html text/html application/pdf application/pdf text/html text/html application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/html image/png image/png image/png image/png image/gif image/png image/png image/png image/jpeg image/gif image/png image/png image/png image/gif image/png image/png image/png image/png image/png image/png image/gif image/png image/png image/gif image/gif image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/jpeg image/gif image/png image/jpeg image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/png image/png image/jpeg image/gif image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/png image/gif application/octet-stream image/gif image/gif image/png image/gif image/gif image/gif image/png image/png application/octet-stream image/gif image/gif image/gif image/gif image/png image/gif image/gif application/octet-stream image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png application/rdf+xml; charset=utf-8 text/html image/png image/png image/jpeg image/png image/png image/png image/png image/png text/html text/html Fall 2014 |
| spellingShingle | sperm sperm biology haploid cells sperm development selective forces meiotic cell division protamines fertilization evolutionary analysis reproductive biology spermatogenesis spermatogenic cycle germline mutations FGFR2 gene germ line selection Fragile X syndrome Meiotic recombination sperm bundling Sperm Cooperation sperm competition 260404 Lesch, Bluma (Bibi) George, Renee 7.345 The Science of Sperm, Fall 2014 |
| title | 7.345 The Science of Sperm, Fall 2014 |
| title_full | 7.345 The Science of Sperm, Fall 2014 |
| title_fullStr | 7.345 The Science of Sperm, Fall 2014 |
| title_full_unstemmed | 7.345 The Science of Sperm, Fall 2014 |
| title_short | 7.345 The Science of Sperm, Fall 2014 |
| title_sort | 7 345 the science of sperm fall 2014 |
| topic | sperm sperm biology haploid cells sperm development selective forces meiotic cell division protamines fertilization evolutionary analysis reproductive biology spermatogenesis spermatogenic cycle germline mutations FGFR2 gene germ line selection Fragile X syndrome Meiotic recombination sperm bundling Sperm Cooperation sperm competition 260404 |
| url | https://hdl.handle.net/1721.1/148324 |
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