7.340 Regenerative Medicine: from Bench to Bedside, Spring 2010
Regenerative medicine involves the repair and regeneration of tissues for therapeutic purposes, such as replacing bone marrow in leukemia, cartilage in osteoarthritis or cells of the heart after a heart attack. In this course, we will explore basic mechanisms of how cells differentiate into specific...
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| Format: | Learning Object |
| Language: | en-US |
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2023
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| Online Access: | https://hdl.handle.net/1721.1/148333 |
| _version_ | 1826198706307727360 |
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| author | Simic, Petra |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Simic, Petra |
| author_sort | Simic, Petra |
| collection | MIT |
| description | Regenerative medicine involves the repair and regeneration of tissues for therapeutic purposes, such as replacing bone marrow in leukemia, cartilage in osteoarthritis or cells of the heart after a heart attack. In this course, we will explore basic mechanisms of how cells differentiate into specific tissues in response to a variety of biologic signaling molecules. We will discuss the use of such factors for in vitro tissue production. We will also study the cellular mechanisms involved in the cloning of animals and how Scottish researchers produced the sheep Dolly using the nucleus of a mammary gland cell from an adult sheep. We will read papers describing organ production, such as the in vitro formation of beating heart cells. We will also consider the molecular bases of cellular tissue remodeling to correct these changes. We will discuss how studies of the developmental, cellular and molecular biology of regeneration have led to the discovery of new drugs. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. |
| first_indexed | 2024-09-23T11:08:50Z |
| format | Learning Object |
| id | mit-1721.1/148333 |
| institution | Massachusetts Institute of Technology |
| language | en-US |
| last_indexed | 2025-03-10T09:26:42Z |
| publishDate | 2023 |
| record_format | dspace |
| spelling | mit-1721.1/1483332025-02-26T21:25:36Z 7.340 Regenerative Medicine: from Bench to Bedside, Spring 2010 Regenerative Medicine: from Bench to Bedside Simic, Petra Massachusetts Institute of Technology. Department of Biology regenerative medicine tissue repair cell differentiation stem cells 260207 Regenerative medicine involves the repair and regeneration of tissues for therapeutic purposes, such as replacing bone marrow in leukemia, cartilage in osteoarthritis or cells of the heart after a heart attack. In this course, we will explore basic mechanisms of how cells differentiate into specific tissues in response to a variety of biologic signaling molecules. We will discuss the use of such factors for in vitro tissue production. We will also study the cellular mechanisms involved in the cloning of animals and how Scottish researchers produced the sheep Dolly using the nucleus of a mammary gland cell from an adult sheep. We will read papers describing organ production, such as the in vitro formation of beating heart cells. We will also consider the molecular bases of cellular tissue remodeling to correct these changes. We will discuss how studies of the developmental, cellular and molecular biology of regeneration have led to the discovery of new drugs. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. 2023-03-06T17:00:07Z 2023-03-06T17:00:07Z 2010-06 2023-03-06T17:00:13Z Learning Object 7.340-Spring2010 7.340 IMSCP-MD5-7394d67b5a7b5e2603787a2fc592a674 https://hdl.handle.net/1721.1/148333 en-US This site (c) Massachusetts Institute of Technology 2023. 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Attribution-NonCommercial-ShareAlike 3.0 Unported http://creativecommons.org/licenses/by-nc-sa/3.0/ text/plain text/html image/png image/jpeg text/html text/html text/html text/html text/html application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/html image/png image/png image/png image/png image/gif image/png image/png image/png image/jpeg image/gif image/png image/png image/png image/gif image/png image/png image/png image/png image/png image/png image/gif image/png image/png image/gif image/gif image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/jpeg image/gif image/png image/jpeg image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/png image/png image/jpeg image/gif image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/png image/gif application/octet-stream image/gif image/gif image/png image/gif image/gif image/gif image/png image/png application/octet-stream image/gif image/gif image/gif image/gif image/png image/gif image/gif application/octet-stream image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png application/rdf+xml; charset=utf-8 text/html image/png image/png image/jpeg image/png image/png image/png image/png image/png text/html text/html Spring 2010 |
| spellingShingle | regenerative medicine tissue repair cell differentiation stem cells 260207 Simic, Petra 7.340 Regenerative Medicine: from Bench to Bedside, Spring 2010 |
| title | 7.340 Regenerative Medicine: from Bench to Bedside, Spring 2010 |
| title_full | 7.340 Regenerative Medicine: from Bench to Bedside, Spring 2010 |
| title_fullStr | 7.340 Regenerative Medicine: from Bench to Bedside, Spring 2010 |
| title_full_unstemmed | 7.340 Regenerative Medicine: from Bench to Bedside, Spring 2010 |
| title_short | 7.340 Regenerative Medicine: from Bench to Bedside, Spring 2010 |
| title_sort | 7 340 regenerative medicine from bench to bedside spring 2010 |
| topic | regenerative medicine tissue repair cell differentiation stem cells 260207 |
| url | https://hdl.handle.net/1721.1/148333 |
| work_keys_str_mv | AT simicpetra 7340regenerativemedicinefrombenchtobedsidespring2010 AT simicpetra regenerativemedicinefrombenchtobedside |