7.343 A Love-Hate Relationship: Cholesterol in Health and Disease, Fall 2005

In this class, we will examine cholesterol's role in the cell and in the body as a whole, from its function as a structural component of the membrane to its function in signaling. We will discuss mechanisms of cholesterol sensing, mechanisms of feedback regulation in cells, cholesterol in the b...

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Main Author: Yesilaltay, Ayce
Language:en-US
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/1721.1/148334
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author Yesilaltay, Ayce
author_facet Yesilaltay, Ayce
author_sort Yesilaltay, Ayce
collection MIT
description In this class, we will examine cholesterol's role in the cell and in the body as a whole, from its function as a structural component of the membrane to its function in signaling. We will discuss mechanisms of cholesterol sensing, mechanisms of feedback regulation in cells, cholesterol in the brain, cholesterol in the circulation, 'good cholesterol' and 'bad cholesterol,' cholesterol-related human disorders, and the drugs that deal with some of these disorders. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
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spelling mit-1721.1/1483342023-03-07T03:58:29Z 7.343 A Love-Hate Relationship: Cholesterol in Health and Disease, Fall 2005 A Love-Hate Relationship: Cholesterol in Health and Disease Yesilaltay, Ayce cholesterol biosynthesis LDL HDL Smith-Lemli-Opitz Syndrome uptake endocytosis hypercholesterolemia atherosclerosis plaque statins HMG-CoA ezetimibe heart attack lipoprotein Fibrates receptor alzheimer's 260806 Human/Medical Genetics In this class, we will examine cholesterol's role in the cell and in the body as a whole, from its function as a structural component of the membrane to its function in signaling. We will discuss mechanisms of cholesterol sensing, mechanisms of feedback regulation in cells, cholesterol in the brain, cholesterol in the circulation, 'good cholesterol' and 'bad cholesterol,' cholesterol-related human disorders, and the drugs that deal with some of these disorders. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. 2023-03-06T17:01:15Z 2023-03-06T17:01:15Z 2005-12 2023-03-06T17:01:22Z 7.343-Fall2005 7.343 IMSCP-MD5-eed3470b2dc64b015eb3f2c058fb7e3d https://hdl.handle.net/1721.1/148334 en-US This site (c) Massachusetts Institute of Technology 2023. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions. Attribution-NonCommercial-ShareAlike 3.0 Unported http://creativecommons.org/licenses/by-nc-sa/3.0/ text/plain text/html image/jpeg image/jpeg text/html text/html text/html text/html text/html application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream application/octet-stream text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/css text/html image/png image/png image/png image/png image/gif image/png image/png image/png image/jpeg image/gif image/png image/png image/png image/gif image/png image/png image/png image/png image/png image/png image/gif image/png image/png image/gif image/gif image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/jpeg image/gif image/png image/jpeg image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/png image/png image/jpeg image/gif image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/gif image/png image/gif application/octet-stream image/gif image/gif image/png image/gif image/gif image/gif image/png image/png application/octet-stream image/gif image/gif image/gif image/gif image/png image/gif image/gif application/octet-stream image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png image/png application/rdf+xml; charset=utf-8 text/html image/png image/png image/jpeg image/png image/png image/png image/png image/png text/html text/html Fall 2005
spellingShingle cholesterol
biosynthesis
LDL
HDL
Smith-Lemli-Opitz Syndrome
uptake
endocytosis
hypercholesterolemia
atherosclerosis
plaque
statins
HMG-CoA
ezetimibe
heart attack
lipoprotein
Fibrates
receptor
alzheimer's
260806
Human/Medical Genetics
Yesilaltay, Ayce
7.343 A Love-Hate Relationship: Cholesterol in Health and Disease, Fall 2005
title 7.343 A Love-Hate Relationship: Cholesterol in Health and Disease, Fall 2005
title_full 7.343 A Love-Hate Relationship: Cholesterol in Health and Disease, Fall 2005
title_fullStr 7.343 A Love-Hate Relationship: Cholesterol in Health and Disease, Fall 2005
title_full_unstemmed 7.343 A Love-Hate Relationship: Cholesterol in Health and Disease, Fall 2005
title_short 7.343 A Love-Hate Relationship: Cholesterol in Health and Disease, Fall 2005
title_sort 7 343 a love hate relationship cholesterol in health and disease fall 2005
topic cholesterol
biosynthesis
LDL
HDL
Smith-Lemli-Opitz Syndrome
uptake
endocytosis
hypercholesterolemia
atherosclerosis
plaque
statins
HMG-CoA
ezetimibe
heart attack
lipoprotein
Fibrates
receptor
alzheimer's
260806
Human/Medical Genetics
url https://hdl.handle.net/1721.1/148334
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