Dysfunctional tRNA reprogramming and codon-biased translation in cancer
Many cancers hijack translation to increase the synthesis of tumor-driving proteins, the messenger mRNAs of which have specific codon usage patterns. Termed 'codon-biased translation' and originally identified in stress response regulation, this mechanism is supported by diverse studies de...
Main Authors: | Dedon, Peter C, Begley, Thomas J |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2023
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Online Access: | https://hdl.handle.net/1721.1/148492 |
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