Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells
Children with autism spectrum disorders often display dysregulated immune responses and related gastrointestinal symptoms. However, the underlying mechanisms leading to the development of both phenotypes have not been elucidated. Here, we show that mouse offspring exhibiting autism-like phenotypes d...
Main Authors: | Kim, Eunha, Paik, Donggi, Ramirez, Ricardo N, Biggs, Delaney G, Park, Youngjun, Kwon, Ho-Keun, Choi, Gloria B, Huh, Jun R |
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Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2023
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Online Access: | https://hdl.handle.net/1721.1/148689 |
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