Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery (MINDDS): a single-centre, parallel-arm, randomised, placebo-controlled superiority trial

Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery (MINDDS): a single-centre, parallel-arm, randomised, placebo-controlled superiority trial

BACKGROUND: The delirium-sparing effect of nighttime dexmedetomidine has not been studied after surgery. We hypothesised that a nighttime dose of dexmedetomidine would reduce the incidence of postoperative delirium as compared to placebo. METHODS: This single-centre, parallel-arm, randomised, placeb...

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Bibliographic Details
Main Authors: Qu, Jason Z, Mueller, Ariel, McKay, Tina B, Westover, M Brandon, Shelton, Kenneth T, Shaefi, Shahzad, D'Alessandro, David A, Berra, Lorenzo, Brown, Emery N, Houle, Timothy T, Akeju, Oluwaseun
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:English
Published: Elsevier BV 2023
Online Access:https://hdl.handle.net/1721.1/148700

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