Intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe
The visual word form area (VWFA), a region canonically located within left ventral temporal cortex (VTC), is specialized for orthography in literate adults presumbly due to its connectivity with frontotemporal language regions. But is a typical, left-lateralized language network critical for the VWF...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Informa UK Limited
2023
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| Online Access: | https://hdl.handle.net/1721.1/148774 |
| _version_ | 1811087926319120384 |
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| author | Li, Jin Kean, Hope Fedorenko, Evelina Saygin, Zeynep |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Li, Jin Kean, Hope Fedorenko, Evelina Saygin, Zeynep |
| author_sort | Li, Jin |
| collection | MIT |
| description | The visual word form area (VWFA), a region canonically located within left ventral temporal cortex (VTC), is specialized for orthography in literate adults presumbly due to its connectivity with frontotemporal language regions. But is a typical, left-lateralized language network critical for the VWFA's emergence? We investigated this question in an individual (EG) born without the left superior temporal lobe but who has normal reading ability. EG showed canonical typical face-selectivity bilateraly but no wordselectivity either in right VWFA or in the spared left VWFA. Moreover, in contrast with the idea that the VWFA is simply part of the language network, no part of EG's VTC showed selectivity to higher-level linguistic processing. Interestingly, EG's VWFA showed reliable multivariate patterns that distinguished words from other categories. These results suggest that a typical left-hemisphere language network is necessary for acanonical VWFA, and that orthographic processing can otherwise be supported by a distributed neural code. |
| first_indexed | 2024-09-23T13:54:05Z |
| format | Article |
| id | mit-1721.1/148774 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T13:54:05Z |
| publishDate | 2023 |
| publisher | Informa UK Limited |
| record_format | dspace |
| spelling | mit-1721.1/1487742023-03-28T03:21:25Z Intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe Li, Jin Kean, Hope Fedorenko, Evelina Saygin, Zeynep Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences The visual word form area (VWFA), a region canonically located within left ventral temporal cortex (VTC), is specialized for orthography in literate adults presumbly due to its connectivity with frontotemporal language regions. But is a typical, left-lateralized language network critical for the VWFA's emergence? We investigated this question in an individual (EG) born without the left superior temporal lobe but who has normal reading ability. EG showed canonical typical face-selectivity bilateraly but no wordselectivity either in right VWFA or in the spared left VWFA. Moreover, in contrast with the idea that the VWFA is simply part of the language network, no part of EG's VTC showed selectivity to higher-level linguistic processing. Interestingly, EG's VWFA showed reliable multivariate patterns that distinguished words from other categories. These results suggest that a typical left-hemisphere language network is necessary for acanonical VWFA, and that orthographic processing can otherwise be supported by a distributed neural code. 2023-03-27T13:41:55Z 2023-03-27T13:41:55Z 2023-01-18 2023-03-27T13:36:42Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/148774 Li, Jin, Kean, Hope, Fedorenko, Evelina and Saygin, Zeynep. 2023. "Intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe." Cognitive Neuropsychology. en 10.1080/02643294.2023.2164923 Cognitive Neuropsychology Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Informa UK Limited Taylor & Francis |
| spellingShingle | Li, Jin Kean, Hope Fedorenko, Evelina Saygin, Zeynep Intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe |
| title | Intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe |
| title_full | Intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe |
| title_fullStr | Intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe |
| title_full_unstemmed | Intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe |
| title_short | Intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe |
| title_sort | intact reading ability despite lacking a canonical visual word form area in an individual born without the left superior temporal lobe |
| url | https://hdl.handle.net/1721.1/148774 |
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