Local Rules Modeling of Nucleation-Limited Virus Capsid Assembly

We describe an application of computer modeling to the study of the kinetics of virus capsid (protein shell) assembly. We examine two proposed models of the source of nucleation-limited growth, an observed growth pattern in which initiation of new capsids occurs significantly more slowly than subun...

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Bibliographic Details
Main Authors: Schwartz, Russell, Prevelige, Peter E., Berger, Bonnie
Published: 2023
Online Access:https://hdl.handle.net/1721.1/149281
Description
Summary:We describe an application of computer modeling to the study of the kinetics of virus capsid (protein shell) assembly. We examine two proposed models of the source of nucleation-limited growth, an observed growth pattern in which initiation of new capsids occurs significantly more slowly than subunit addition onto initiated capsids.