Local Rules Modeling of Nucleation-Limited Virus Capsid Assembly

We describe an application of computer modeling to the study of the kinetics of virus capsid (protein shell) assembly. We examine two proposed models of the source of nucleation-limited growth, an observed growth pattern in which initiation of new capsids occurs significantly more slowly than subun...

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Main Authors: Schwartz, Russell, Prevelige, Peter E., Berger, Bonnie
Published: 2023
Online Access:https://hdl.handle.net/1721.1/149281
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author Schwartz, Russell
Prevelige, Peter E.
Berger, Bonnie
author_facet Schwartz, Russell
Prevelige, Peter E.
Berger, Bonnie
author_sort Schwartz, Russell
collection MIT
description We describe an application of computer modeling to the study of the kinetics of virus capsid (protein shell) assembly. We examine two proposed models of the source of nucleation-limited growth, an observed growth pattern in which initiation of new capsids occurs significantly more slowly than subunit addition onto initiated capsids.
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spelling mit-1721.1/1492812023-03-30T03:07:08Z Local Rules Modeling of Nucleation-Limited Virus Capsid Assembly Schwartz, Russell Prevelige, Peter E. Berger, Bonnie We describe an application of computer modeling to the study of the kinetics of virus capsid (protein shell) assembly. We examine two proposed models of the source of nucleation-limited growth, an observed growth pattern in which initiation of new capsids occurs significantly more slowly than subunit addition onto initiated capsids. 2023-03-29T14:41:06Z 2023-03-29T14:41:06Z 1998-08 https://hdl.handle.net/1721.1/149281 MIT-LCS-TM-584 application/pdf
spellingShingle Schwartz, Russell
Prevelige, Peter E.
Berger, Bonnie
Local Rules Modeling of Nucleation-Limited Virus Capsid Assembly
title Local Rules Modeling of Nucleation-Limited Virus Capsid Assembly
title_full Local Rules Modeling of Nucleation-Limited Virus Capsid Assembly
title_fullStr Local Rules Modeling of Nucleation-Limited Virus Capsid Assembly
title_full_unstemmed Local Rules Modeling of Nucleation-Limited Virus Capsid Assembly
title_short Local Rules Modeling of Nucleation-Limited Virus Capsid Assembly
title_sort local rules modeling of nucleation limited virus capsid assembly
url https://hdl.handle.net/1721.1/149281
work_keys_str_mv AT schwartzrussell localrulesmodelingofnucleationlimitedviruscapsidassembly
AT preveligepetere localrulesmodelingofnucleationlimitedviruscapsidassembly
AT bergerbonnie localrulesmodelingofnucleationlimitedviruscapsidassembly