Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer’s disease

Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer’s disease

Complex diseases are characterized by spatiotemporal cellular and molecular changes that may be difficult to comprehensively capture. However, understanding the spatiotemporal dynamics underlying pathology can shed light on disease mechanisms and progression. Here we introduce STARmap PLUS, a method...

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Bibliographic Details
Main Authors: Zeng, Hu, Huang, Jiahao, Zhou, Haowen, Meilandt, William J, Dejanovic, Borislav, Zhou, Yiming, Bohlen, Christopher J, Lee, Seung-Hye, Ren, Jingyi, Liu, Albert, Tang, Zefang, Sheng, Hao, Liu, Jia, Sheng, Morgan, Wang, Xiao
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/150033

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