The neuronal pentraxin Nptx2 regulates complement activity and restrains microglia-mediated synapse loss in neurodegeneration
<jats:p>Complement overactivation mediates microglial synapse elimination in neurological diseases such as Alzheimer’s disease (AD) and frontotemporal dementia (FTD), but how complement activity is regulated in the brain remains largely unknown. We identified that the secreted neuronal pentrax...
| 主要な著者: | , , , , , , , , , , |
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| その他の著者: | |
| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
American Association for the Advancement of Science (AAAS)
2023
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| オンライン･アクセス: | https://hdl.handle.net/1721.1/150035 |