Epistasis at the SARS-CoV-2 Receptor-Binding Domain Interface and the Propitiously Boring Implications for Vaccine Escape

Epistasis at the SARS-CoV-2 Receptor-Binding Domain Interface and the Propitiously Boring Implications for Vaccine Escape

<jats:p>Emergence of vaccine escape variants of SARS-CoV-2 is arguably the most pressing problem during the COVID-19 pandemic as vaccines are distributed worldwide. We employed a computational approach to assess the risk of antibody escape resulting from mutations in the receptor-binding domai...

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Bibliographic Details
Main Authors: Rochman, Nash D, Faure, Guilhem, Wolf, Yuri I, Freddolino, Peter L, Zhang, Feng, Koonin, Eugene V
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:English
Published: American Society for Microbiology 2023
Online Access:https://hdl.handle.net/1721.1/150406

Internet

https://hdl.handle.net/1721.1/150406

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